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KMID : 0383819870340010057
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Tuberculosis and Respiratory Diseases
1987 Volume.34 No. 1 p.57 ~ p.62
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Fungal Complication in Long Term Hospitalized Patients with Pulmonary Tuberculosis
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이석기(李奭基)/Seok Ki Lee
김상재(金尙材)/Sang Jae Kim
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Abstract
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An investigation into fungal complication in long term hospitalized patients (173) with
pulmonary tuberculosis in Seoul City Seodaemoon Hospital has been made by
immunodiffusion tests, sputum culture, and chest radiography.
Precipitating antibodies to the antigens of filamentous fungi were detected in sera
from 25 patients (14.5%) and a definite or suspected fungus ball shadows were seen in
chest X-rays of 8 patients of which one was apparently formed by A. flavus and all the
others by A. fumigatus. Most commonly involved species was A. fumigatus(11.0%) P.
boydii and A. nidulans were involved in one and four cases respectively. Positive
immunodiffusion to filamentous fungal antigens were more common in sputum negative
(tubercle bacilli) patients and most often in cases with sputum negative cavities. Some
patients produced precipitin bands to more than one species mainly due to cross
reactivity of antigens and rarely due to mixed infection with some other fungi.
The 13 patients showed a positive reaction to C. albicans, which was more common
in bacillary cases than in abacillary cases, however their relevance to the clinical
symptoms could not be determined.
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